Octopus UK “megatrial” will test existing drugs as new treatments for MS


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4 April 2023 The first patients have been recruited for a revolutionary trial, led by UCL researchers, that will transform the way that treatments are tested for progressive multiple sclerosis (MS). Octopus is a world-first clinical trial, funded by the MS Society and led by researchers at the MRC Clinical Trials Unit at UCL.


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Octopus is a clinical trial evaluating several potential treatments for primary and secondary progressive multiple sclerosis (MS).


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Octopus is a revolutionary trial that will transform the way we test treatments for progressive MS. A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster.


This octopus learned to use a camera faster than some humans The Independent The Independent

Monday 14 November 2022 Octopus is a new clinical trial for primary and secondary progressive MS. After some delays, it's now had the official thumbs up from the regulators. This important milestone brings us another step closer to the trial getting started.


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Inside the MS Octopus mega-trial: inspired by cancer, supported by patients Features Inside the MS mega-trial: inspired by cancer, supported by patients The UK MS Society discusses how it plans to research treatments for progressive MS. Kezia Parkins June 23, 2021


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Jeremy Chataway, MA, PhD, FRCP, UCL Institute of Neurology, London, UK, gives an insight into the Octopus trial, the first-ever multi-arm, multi-stage (MAMS).


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Introducing Octopus - the world's first multi-arm, multi-stage trial for MS Tuesday 4 May 2021 We're pleased to introduce Octopus - our revolutionary, multi-arm, multi-stage trial that will transform the way we test treatments for progressive MS.


Octopus inside the progressive MS megatrial VJNeurology

Octopus will test several experimental MS therapies against a shared control group. Treatments that appear effective from early data can continue into the next stage without needing to set up a.


'Major moment in MS research' as new Octopus trial starts Lounge

Octopus is a revolutionary trial that will transform the way we test treatments for Progressive Multiple Sclerosis (MS). A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster. Octopus is now open to recruitment!


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The Octopus trial is led by Prof Jeremy Chataway at University College London (UCL). Along with the trial site at UCL Queen Square Institute of Neurology, the Anne Rowling Clinic is now open for recruitment. The Octopus trial management team have plans to open 30 Octopus trial sites across the UK. The Anne Rowling Regenerative Neurology Clinic.


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A broad-reaching trial of already-approved drugs is hoped to turn up new treatment options for people with progressive forms of MS. Octopus Study to Test Drug Effects on Progressive MS


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The Octopus MS clinical trial is the first multi-arm, multi-stage trial for MS. The trial is led by researchers at University College London and is currently testing two drugs already used in other conditions against a placebo (dummy drug). These are metformin and alpha lipoic acid.


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Octopus is a revolutionary trial that will transform the way we test treatments for progressive MS. A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster. The trial team have now confirmed the first treatments they'll be testing .


Octopus UK “megatrial” will test existing drugs as new treatments for MS

The Octopus trial is intended to accelerate the search for drugs to treat progressive MS by comparing three against the same control group and rolling trial phases together. The design.


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OCTOPUS is the first MS trial to use a type of trial design known as multi-arm multi-stage (MAMS). This method can have many advantages over traditional trials: It allows several treatments to be tested at the same time against a common control (i.e. "multi-arm"). Treatments which appear to be effective from the early data can continue onto.


Octopuses Get Emotional About Pain, Research Suggests Mind Matters

Launched in April 2023, Octopus is a revolutionary MS clinical trial that will transform the way we test treatments for progressive MS. The trial is devised to be smarter than the current standard style of clinical trial.

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